Synthetic Development

Experts in Originating & Polishing Synthetic Routes

The scientists at Cascade Chemistry are experts in originating and polishing synthetic routes.

We are particularly experienced at devising methods to obtain kilograms of material which previously had been made only on milligram scale. Our work has frequently served as the basis for large-scale manufacturing. We employee a number of experienced process chemists, medicinal chemists, and analytical chemists formally from pharma and larger CMOs.

Much of the development work focuses on transfer of a new API from Med-Chem into practical scale-up. Our experts will explore new routes to the desired materials, optimize current processes, or transfer as is for rapid scale up as needed. The analytical team works with the synthetic chemists early on to identify potential issues such as stability, yields, or interference with impurities or degradants. 

If you’d like to receive an estimate or discuss a project, call us at 541-484-2387 or contact us by clicking here.

synthetic development